NMN Supplements: Before & After Results

When it comes to health and wellness, there really are no quick fixes. And in the case of NMN, or nicotinamide mononucleotide, that’s actually a good thing. NMN supplementation is intended to gradually restore NAD, or nicotinamide adenine dinucleotide, an oh-so-important enzyme that maintains cellular function. The older we get, the less NAD we have and the more aging-related side effects we experience—more greys, more wrinkles, slower recovery times, a fuzzier mind, all the things we typically chalk up to simply getting older. This is also when serious issues, like heart conditions, diabetes, dementia, cancer and chronic pain and inflammation, begin making their presence known. And it’s no coincidence. The good news? As an NAD precursor, NMN is an easy and proven way to not only slow this decline, but actually reverse it.

Of course, the proof is in the pudding. Science has shown tremendous benefits directly associated with NMN supplementation, but what about the typical consumer? Here at Wonderfeel, we’ve heard from hundreds of customers who are seeing and feeling incredible results in the form of better focus, more energy, and more restful sleep, among other benefits. These changes begin on a cellular level, which means it takes time for measurable results to become detectable. And consistency is key—the idea is to restore NAD in the cells, and that’s not a one-and-done scenario. Now, if you’re wondering what exactly you can expect from supplementing with NMN, you aren’t alone. NAD and NMN are on people’s radars these days—and we love it!—and many of them are specifically researching real-life results in the form of NMN before and afters. Let’s clarify expectations with key benefits, typical timelines, and most importantly, before-and-after results from real people just like you.

What’s so great about supplementing with NMN?

That’s an excellent question. And to answer it, let’s back up to explain a little more about NAD. To call it “terribly important” is actually underselling it, because this enzyme is absolutely essential in every living thing. Dr. Andrew Salzman, the chief medical officer here at Wonderfeel, describes this small molecule as “the centerpiece of biology” for three critical functions. Let’s review.

NAD = energy

NAD directly controls the production of ATP, which, as Dr. Salzman puts it, is the currency we use in order to think, to move our muscles, to digest and metabolize food—basically, any and everything you do on any given day. Low NAD means low energy, period, full stop.

Antioxidant defense

Number two is NAD’s pivotal role as a bodyguard of sorts. It produces the antioxidant defense we so desperately need to ward off never-ending environmental attacks. To live in an oxygen-rich world, we need antioxidant functionalities in the form of NADPH, and that’s produced by—you guessed it—NAD. 

DNA repair

“Every minute, we are undergoing changes in the DNA because of the environment, because of oxidants and cosmic rays,” says Dr. Salzman. These changes begin as breaks, or knicks, in the strands of our DNA—to the tune of 70 a minute! Our body has an industrious little worker bee that diligently repairs these knicks on the spot, which prevents a mutation when the cells divide. It’s an enzyme known as PARP, and it’s the second most abundant protein in the nucleus. And guess what it needs to do its job properly? Yep, NAD!

How less NAD translates to faster aging

Now, consider the fact that as we age, our production of NAD begins a gradual decline. Given all the ways NAD keeps our bodies operational, it’s more than a little worrisome. This slippery slope begins as early as our 30s, and by the time we hit age 50, we have half the NAD we enjoyed in our 20s. As you might imagine, this has a pretty significant downstream effect. Beyond the three functions we listed above, NAD is also used by all sorts of very important enzymes and proteins for different essential functions in the body. Take sirtuins, a family of proteins busily regulating cellular homeostasis to manage things like inflammation and stress management and your 24-hour internal clock. Without NAD, sirtuins are like an engine without oil. As NAD declines, so does sirtuin activity—and that’s another problem.

All of this diminished activity plays out in real time. We’re slower to recover, whether it’s from travel, a workout, or just staying up past our usual bedtime. Our hair is losing its pigment and not growing like it once did. Our skin isn’t as youthful, and we’re seeing things like wrinkles and age spots. Our energy levels are lower—maybe we’re winded after a few flights of stairs or a few laps around the grocery store. We walk into a room and can’t remember why. In short, we’re getting older, and a not-so-small part of all of it can be directly traced to less NAD in the body and its trickle-down effects.

But here’s the good news (finally). Longevity scientists have figured out that NAD precursors, like NMN or NR (nicotinamide riboside) actually jumpstart NAD production. It’s a boon for healthy aging, effectively rolling back the clock to outstanding effect. Let’s talk about the benefits from more NAD in the body—and how they’re translating in the real world.

Big energy gains

When it comes to real-life results, a noticeable difference in energy is a pretty typical early sign that NAD production is back, baby! Here’s how one happy Wonderfeel customer puts it:

“The best thing I’ve noticed since taking 2 capsules every morning is my energy has doubled! I find that I don’t need coffee to wake up anymore. It’s an awesome feeling and I have a lot more energy to play with my toddler grandchildren too! I’m 63 and a runner.” ~Cara B.

Cara’s experience is echoed by mountains of anecdotal evidence, which is backed up by clinical research. Mice studies show that endurance and stamina increase by up to a whopping 80% with NMN, while a small human trial conducted with 48 amateur runners found that NMN supplementation increased aerobic capacity during exercise.

More energy may also be a fringe benefit of other anecdotal NMN benefits, such as faster recovery times, better sleep and fewer aches and pains. If you’re sleeping better and generally feeling better, it stands to reason that you’re going to feel a little more energized, right? Remember the positive feedback loop that comes from feeling good enough to be active—the more you move, the more energy you have, and the more you want to keep moving.

Healthy aging & longevity

This is the big motivator for most people. By increasing NAD levels, NMN can actually help slow down the aging process. Remember, more NAD is associated with better cellular function, enhanced energy metabolism, and improved repair to DNA damage. Now, are we saying that supplementing with NMN means you’ll live to be 120? Well, no (not yet!). But it does mean a marked difference between your biological age and your chronological age. The latter is the literal number of years you’ve passed on this earth. But the former is the true reflection of those years and the toll our bodies and minds have taken in the process. And boosting NAD with NMN supplementation is proving to be a simple yet significant strategy for keeping that biological age far lower than your chronological age, which is all about increasing health span.

How this translates in real life is as individual as you are. Some people notice more energy and quicker recovery times, and it makes them feel younger. Others find that they’ve lost that confounded brain fog and are back to completing the crossword puzzle (in pen, no less!), just like they used to do. “Feeling younger” is pretty personal, but we’re seeing plenty of positive feedback:

“I have been using the Wonderfeel Youngr™ NMN for several months now after thoroughly researching the science. I must say I have not felt this well for years. I am approaching 70 years of age and am more active, have much better cognitive abilities, and am back to weight training after a long hiatus. I am looking forward to new developments in this area of aging biology.” ~Mark W.

“I’m a 65 year old man who loves to cycle. Since taking these Wonderfeel Youngr™ NMN pills I’ve noticed a boost in stamina & power. I can pedal my single speed bike with more virility and an ongoing drive that lasts longer. Truly do feel younger.” ~Paul L.

“After the second month, I noticed my hands weren’t as stiff while playing my acoustic guitar. This was a big deal from the get-go because my tendonitis was accelerating after joining a band. Another highlight is an overall feeling of Zen. I don’t know if this is the result of less pain, but I’m also not going to overthink it. I’ve been taking Youngr™ for almost 9 months now and truly feel like a younger version of myself. I can’t imagine going back to my irritable old normal.” ~Elizabeth S.

Skin deep

There’s no denying that our skin changes when we age. That plump, unlined, baby-soft skin begins to show wear and tear, and some people spend thousands on products and treatments in an effort to, well, look younger. Turns out, the decline in NAD is quite the contributor to those wrinkles and the loss of radiance. As NAD’s ability to manage cellular energy and DNA repair slows, so does the youthfulness of our skin. But we’re hearing rave reviews from people who are seeing big differences:

“Since beginning Wonderfeel, I have received multiple compliments about how great my skin looks. (One long-time friend even asked if I’d had injections!)” ~Laura B.

“Its transformative effects have not only heightened my energy levels but also gives my skin a radiant glow and newfound suppleness.” ~Han G.

Research confirms the benefits of more NAD for better skin. In one Japanese study, researchers found that NMN supplementation in postmenopausal women had a significant improvement on metabolic, hormonal, and skin health. Studies also show that NMN supplementation offers very real, very visible benefits to the skin by supporting skin hydration for a firmer, more elastic appearance. And in very exciting news, many people report a reduction in age spots!

“I’ve been using Wonderfeel for two months now. The age spots on the side of my face have all but disappeared, and they had been pretty pronounced.” ~Suzanne S.

“My husband and I took it for a month, and I feel that my hair has increased a lot, my skin has become smoother, and the spots on my face have lightened. He feels that the gray hair is less.” ~Qiang W.

More good hair days

Some people take NMN specifically to promote new hair growth and keep greys at bay—and it’s working.

“My hair looks and feels healthier and more luxurious, and my nails have never been so strong and beautiful. I am enjoying greater mental clarity and my memory is better than it’s been in years. I love Wonderfeel!” ~Carol S.

“Six months of using Wonderfeel. My graying hair has returned to being its original brown, no gray visible.” ~Lolita Ann C.

“After 3 months of use…my nails grow faster than ever and the roots of my hair seem darker, more vibrant…life seems more sturdy overall.” ~Anonymous

Turns out, diminished or damaged hair follicle activity—the culprit behind thinning, lackluster locks—is one of the side effects of less NAD in the body, and it’s largely related to oxidative stress. Increasing NAD means enhanced cellular function to combat that stress and support cell regeneration, which can help promote healthy hair growth. Supplementing with a product like Youngr™ NMN also appears to benefit the scalp, thanks to reduced inflammation and enhanced blood flow, which brings nutrients and oxygen to hair follicles.

Our Youngr™ formula includes key antioxidants that add their own defenses against oxidative stress and inflammation, which are key for healthy hair. Ergothioneine helps maintain cellular health, which can contribute to hair vitality, while resveratrol actively promotes hair growth by activating a specific pathway responsible for hair follicle development.

As for greying locks, anecdotal evidence and rodent studies alike suggest that NMN supplements may indeed have a positive effect. It relates to what makes hair lose its color in the first place. Oxidative stress damages melanocytes in the hair follicles, which is where melanin is produced—the source of your hair’s color. Meanwhile, reduced antioxidant defenses are often the reason for premature greying. NMN supplements, as we know, help manage oxidative stress and regulate cell regeneration, and it seems that plays out particularly well on our heads!

NMN benefits: What’s the timeframe?

We would love to tell you that detectable results from NMN supplements like Wonderfeel Youngr™ are evident from the get-go, but that’s just not how it works. Think of it this way: By the time you begin supplementing with NMN to increase NAD in your body, your organs and cells have been working less for anywhere from a few years to decades. You’re rebuilding those NAD stores from the moment you take your first oral capsule, but it all begins at a cellular level and it takes time to feel and see results.

That means there really is no specific timeline for results, but we can offer generalities based on feedback from Wonderfeel customers. We hear from many people who are on their NMN journey for the long haul and noticing benefits after a year. Many report dramatic improvements to skin and hair, such as the complete disappearance of chronic eczema and age spots, a return to their original hair color, and thicker eyelashes.

Short-term benefits are also possible, and one of the more immediate benefits is a positive effect on inflammation. We hear from runners who are enormously pleased to notice a reduction in knee pain right away, for example. An uptick in energy and sleep quality also seem to be among the earliest noticed benefits, anywhere in the first few months—and even weeks!—of daily supplementation. Some people find their mind feels a little sharper, and greater levels of endurance and quicker recovery times are often reported in the first six months or so as well. Individual results vary, of course, and have a lot to do with your age and health status. The key is recognizing that NMN supplements, like anything that you do for your health, aren’t a one-time thing. To reap the benefits, be prepared to stay the course! That means two Wonderfeel Youngr™ capsules a day, every day.

The bottom line

NMN really is changing how we age, and people are seeing and feeling the difference for themselves. In the words of one Wonderfeel customer, “Ever since I started using Wonderfeel Youngr™, I feel exactly as the product’s name: wonderful and younger.” Real results from real people like this are a great way of learning about the benefits of NMN supplements—second only to trying them out yourself.