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Muscle Recovery: How NMN Helps Adults Combat Physical Stress

Luis Cifuentes MD

Medically reviewed by Luis Cifuentes MDDr. Cifuentes is a professor, medical doctor, and clinical pharmacologist with over 25 years of experience.

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Clinical studies show NMN enhances muscle recovery and physical performance in adults, particularly the elderly. It works by boosting NAD and nutrient supply to muscles and even aids in faster recuperation from metabolic stress. Additionally, NMN can prevent age-related muscle loss and contribute to a more active lifestyle.

Key Takeaways

  • Among its many benefits for longevity, NMN helps improve physical recovery from things like exercise and injury, jet lag, even a late night out drinking.
  • NMN boosts NAD levels in the body, which helps your muscles get the energy they need to repair and rebuild. In other words, NMN helps the body bounce back from physical stress more easily and even fights age-related muscle loss.
  • Less NAD often means higher fatigue levels, less physical strength, a loss of muscle mass and extended recovery times—but the reverse is true, too.

Hitting the half-century mark brings wisdom and freedom, but it also comes with some sneaky biological challenges. Bone density loss and muscle mass decline set in and sedentary lifestyles can accelerate this. This leads to slower recovery times than in our younger years. Now for the good news –  NMN can be a game changer in recovering from physical stress, and sore muscles. Here’s why.

Stronger, and faster recovery with NMN

Animal studies laid the groundwork for the idea that increasing NAD in the body can improve physical performance and recovery by boosting blood and nutrient supply to the muscles. Clinical studies with humans are confirming it. A 2021 study looked at the effects of an oral dose of 250 mg of NMN – a precursor to NAD – per day in men over 65 for twelve weeks. Not only did NMN increase NAD levels, but renewed muscle strength led to better performance. This was demonstrated in walking speed, grip strength, and how many times participants could rise from a seated to a standing position in 30 seconds.

The most recent clinical trial looked at the effects of NMN on humans. It likewise saw significant improvement in NAD blood levels and a walking endurance test. Notably, there was an impressive upswing in muscle performance with higher doses of NMN, specifically at the 900 mg mark.

How else can NMN help?

NMN has been generating quite a buzz for its multifaceted benefits, with muscle recovery being one of its standout talents. But its abilities don’t stop there! Recovery, in the context of NMN, isn’t just about bouncing back after flexing those muscles during a grueling workout. Recuperating faster from things like jet lag, a particularly late night, or too much alcohol is pretty commonly reported. That makes sense – both fall into the realm of metabolic stress, something that NMN can also address. More studies are needed, but it would appear that with alcohol in particular, NMN can have a modulating effect because of its impact on the liver. In fact, NMN is being explored as a way to reduce the liver damage associated with chronic alcohol consumption.

Cocktail and jet with contrail shows NMN for hangovers, jetlag, and more than just muscle recovery

The effects of NAD on jet lag have also been studied, with researchers finding it may counteract the effects on cognition and sleepiness. Keep that in mind next time you catch an overseas flight or pull an all-nighter!

It’s not just slower recovery times that come with aging. Muscle loss is inevitable, something that can largely be traced to mitochondrial dysfunction and a decrease in adenosine triphosphate (ATP) production. ATP has a big job in the cells of living organisms—hello muscle tissue—and it needs plenty of NMN to thrive. Think of ATP as a sort of storage locker for energy that’s produced by the mitochondria. When the cell needs energy, it opens the storage locker to release various molecules, including NAD. So, yes, NMN can play a significant role in inhibiting the loss of muscle as we age providing a renewed feeling that can help keep you active.

A slowing of mitochondrial function has a dampening effect on ATP and NAD production. This is problematic for many reasons, including the fact that NAD is itself critical for mitochondrial function. A decline in NAD contributes to what we consider the aging process. In terms of physical performance, we see it played out in things like higher fatigue levels, a drop in body strength, declining muscle mass, and, yes, reduced recovery times from physical activity. That’s in addition to other age-related conditions that begin popping up as these systems slow and NAD production nosedives, such as metabolic disorders, heart disease, and cognitive decline.

The NMN energy recovery connection

The fact is that the less we move, the less we want to move, the more tired we feel, and the longer it takes to feel better if we do move. It seems counterintuitive, but low energy levels are intrinsically tied to inactivity. That’s because we need oxygen to produce energy, and sedentary lifestyles limit oxygen to the brain and body, which means a big energy dump.

Fortunately, the reverse is true as well – the more we move, the more energy we have, and the more resilient our muscles and tendons become, even in our later years. There are all sorts of benefits of physical activity for older adults, which is why experts everywhere are so adamant about staying active. It truly keeps us youthful, and that’s in no small part to the fact that exercise naturally increases NAD levels in the body, which, again, stimulates mitochondrial production. 

There are no hard and fast rules when it comes to your own physical plan of action. “The recommended type, frequency, and exercise intensity will vary depending on age, endurance levels, and medical history”, says personal trainer Dr. Mikulsky in Total Shape. Her suggestion is to exercise with enough intensity that it becomes slightly challenging to hold a conversation with a friend. So, if you’re able to have a full-blown discussion about your favorite TV show, you may need to up the intensity a bit!

Strong yogi man on vivid orange background recovered with NMN

As we embrace active lifestyles, recovering from vigorous or even moderate activities can feel like trying to catch a gust of wind, especially as we get older. But with NMN, we can harness the power of the breeze and propel ourselves toward optimal muscle recovery. It goes without saying that the more NAD we have, the better. Fortunately, a daily dose of NMN, like our own Wonderfeel Youngr, makes it easy.

Frequently Asked Questions

Does NMN increase muscle?

NMN doesn’t directly build muscle. But by boosting NAD in the body, NMN gives your muscles the energy they need to repair, which helps them grow stronger after every workout. That energy also helps fight age-related muscle loss, making NMN for physical performance a win-win.

Does NAD help with muscle growth?

NAD can help with muscle growth. It gives muscles the energy they need to repair and grow after exercise. The more NAD you have, the faster you can recover and the more efficiently your muscles can work. That’s how you build stronger muscles over time.

Does NAD affect testosterone?

NAD may have an indirect effect on testosterone because it supports energy production and cell function in the cells that produce testosterone. That helps create a better environment for testosterone production.

Which therapy is best for muscle growth?

Strength training, a high-protein diet and plenty of recovery time is the best therapy for muscle growth. Strength training helps stimulate muscle growth, protein provides the building blocks, and rest gives your muscles time to repair and grow stronger. Supplements like NMN and creatine can also support muscle recovery and energy levels to help build stronger muscles over time.

Can NAD cause muscle pain?

NAD doesn’t cause muscle pain, but using NMN supplements to increase NAD often leads to more efficient recovery. You might notice temporary muscle soreness after working out, which is a sign that your muscles are repairing and growing. It’s not from the NAD, it’s from your muscles responding to the stress of the exercise.

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