Key Takeaways
- Amazon removed NMN supplements following an FDA letter that retroactively revoked NMN’s status as a dietary supplement, citing ongoing pharmaceutical development—not safety concerns—as the reason.
- The ban ended up removing many low-quality, unregulated NMN products—particularly those from questionable overseas manufacturers—which may ultimately improve consumer safety and product standards.
- Consumers can still access high-quality NMN supplements through trusted brands like Wonderfeel, which use clinically tested, GMP-certified formulations and are committed to science-backed wellness.
- The FDA’s decision is controversial, especially since it prioritizes pharmaceutical interests over consumers’ access to safe and effective supplements.
- Wonderfeel remains committed to keeping NMN accessible outside of Amazon.
What happened?
On February 16th, Amazon sent a message to all NMN companies on its platform. Their letter states, “Products that contain NMN as an ingredient can no longer be sold or distributed as a dietary supplement by manufacturers or retailers in the United States.” This means that Amazon has effectively banned NMN from its website.
What does the Amazon ban on NMN mean to consumers?
Consumers will not be able to buy NMN products on Amazon starting March 2023. This move will surely cause a significant inconvenience for those who rely on Amazon. They will now need to explore other avenues to obtain NMN products.
According to some industry watchdogs, a silver lining can be found in the news. Ultimately, a significant number of imposter brands from Chinese manufacturers will be eliminated. A majority of these brands produce low-grade NMN products in chemical plants with questionable purity levels. The Amazon ban will prevent these sham NMN peddlers from taking advantage of unsuspecting customers. By simply by removing their direct and often only sales channel in the U.S., consumers will be protected against potentially harmful products.
Did Amazon ban NMN due to a safety issue?
No, Amazon’s banning of NMN sales is not related to safety concerns. On November 4, 2022, the FDA issued a controversial letter revoking NMN’s previously assigned status as a dietary supplement and excluding it from the definition. The reason behind this decision is the current investigation of NMN as a potential pharmaceutical drug. As a result, Amazon has decided to remove the sale of NMN products from its platform.
While Amazon’s decision to remove NMN products is unrelated to safety issues, it is worth considering that safety concerns have arisen in the past. Primarily are reports of phony NMN supplements sold mostly on Amazon with inadequate purity levels, no stability studies, and without GMP certification. However, we encourage consumers to remain positive and continue incorporating NMN supplements into their daily health and wellness routine, provided they source them from reputable and trusted sources.
How and where to buy safe NMN products after Amazon’s removal?
We expect that consumers will still be able to find NMN after the Amazon ban. Established brands, such as Wonderfeel Biosciences, possess a deep understanding of NAD precursors and back their supplements with clinical research. These sources are trustworthy, and consumers can rely on them to provide safe and effective NMN products manufactured in GMP-certified facilities.
Why did Amazon ban sales of NMN products at its store?
Amazon is banning sales of NMN products in its stores because of an FDA letter stating that NMN is not considered a dietary supplement as of November 2023. This is a reversal of FDA’s previous decision. Their stated reason is to protect a pharmaceutical drug development application for a patented version of NMN. It’s disheartening that Amazon is putting the interests of the pharmaceutical industry ahead of the health and well-being of its customers who rely on NMN supplements in their daily regimen.
More on the FDA’s Decision
The FDA’s announcement triggered backlash from the wellness and supplement communities. Wonderfeel has been actively consulting legal experts to navigate this evolving situation while ensuring product availability for subscribers and new customers.
Know that our commitment to making a product you’ve come to rely on is unwavering. This is a perfect time to emphasize that safety, science, innovation, and a proactive approach to wellness are at our core.
Our guiding principles
- We take all measures to ensure that our customers receive a safe and stable supplement, tested for purity by accredited third-party labs. We produce our product at facilities in the USA certified for Good Manufacturing Practice (cGMP).
- The NMN sourced for our products is clinically tested in one of the most extensive human clinical trials to date. Based on various health markers, the resulting toxicology report shows that NMN at 900mg per day is well-tolerated.
- We continue to advance the science of NMN. On November 10, we announced an in vitro study of our novel NMN supplement on human cells.
- We believe in an individual’s right to govern their own wellness protocols. We will make our NMN products available outside of the Amazon ban in jurisdictions that protect the rights of consumers above pharmaceutical companies. We will continue sales of NMN as a dietary supplement.
- Countries like Japan have sold NMN as a dietary supplement since 2016. It’s worth noting that this was well before Metro International Biotech LLC, the company mentioned in the FDA’s statement, began conducting research on their NMN derivative in the United States.
A world where everyone wins
- As part of our current preclinical and clinical studies, we are laying the groundwork for Pharma development of our formulations. These can run parallel to our nutraceutical pursuits without infringing on anyone else’s IP or the ability to market our products as dietary supplements. While we advocate for the protection of drug development, we believe that such efforts shouldn’t deprive the public of safe and readily used supplements. We firmly believe that there exist many sustainable business models for the pharmaceutical drug development of NMN and its over-the-counter derivatives.
- In keeping with our founding principle–a proactive approach to health and wellness–we commit to providing publicly available, natural solutions backed by rigorous science. We have observed tens of thousands of Americans safely benefiting from NMN supplements. The ban on NMN sales by Amazon is disheartening for many people who buy their NMN on the platform. We hope that the FDA takes this into consideration by looking out for the public interest, not by taking a safe and efficacious product like NMN out of the hands of consumers like you. Not by taking a safe and efficacious product like NMN out of the hands of consumers like you.
Additional expert perspective
Robert (“Bob”) Durkin, former deputy director of dietary supplements at the FDA (2015–2019), has highlighted the unusual nature of the FDA’s position on NMN. He said, “It’s hard to imagine that’s what Congress intended” when referring to the agency’s retroactive exclusion of NMN from the definition of a dietary supplement after it was already legally on the market. This underscores the regulatory confusion surrounding NMN while reinforcing that this dispute is about classification, not consumer safety or product efficacy.
A 2025 update: NMN, FDA, and what it means for you
What’s the latest on NMN’s regulatory status?
Despite confusion in the headlines, NMN remains accessible in the US, with no FDA-enforced ban in place. The debate is a regulatory dispute about classification—not about safety.
Initially, the FDA allowed NMN sales under a New Dietary Ingredient Notification in 2022 but later reversed its stance, arguing NMN could not be sold as a dietary supplement due to pharmaceutical investigations. This led Amazon to remove NMN products in 2023. However, research continues to support NMN’s safety and benefits for cellular energy and healthy aging.
The legal challenge and what it means for you
In response to the FDA’s decision, the Natural Products Association (NPA) filed a lawsuit and citizen petition, challenging the FDA’s interpretation and seeking to maintain NMN’s availability as a supplement. In November 2024, a court granted a joint motion to stay the case, preventing the FDA from enforcing actions against NMN products during this period.
This means you can continue purchasing high-quality NMN products from trusted brands like Wonderfeel without fear of disruption while the legal process unfolds.
Why this matters
- NMN remains safe, effective, and supported by extensive research.
- The current issue is regulatory confusion, not consumer safety.
- Wonderfeel remains committed to providing clinically tested, GMP-certified NMN supplements you can trust.
The bottom line
NMN supplements remain legal, accessible, and safe. While the FDA’s classification is under review, your ability to use NMN as part of a proactive wellness routine is not at risk. Wonderfeel will continue to advocate for your right to choose high-quality supplements while advancing the science of NMN for healthy aging.
Frequently Asked Questions
The FDA revoked NMN’s status as a dietary supplement because it’s currently being investigated as a potential pharmaceutical drug, but the agency has not asked reputable NMN companies, like Wonderfeel, to remove it from the market. This decision reversed its earlier approval. The decision is intended to protect drug development interests, and it’s not related to any kind of safety concern.
Amazon removed NMN because the FDA revoked its status as a dietary supplement, citing its ongoing investigation as a potential pharmaceutical drug. In response, Amazon chose to remove all NMN products from its platform to comply with this regulatory change—even though the decision wasn’t based on safety concerns.
NMN isn’t banned. The issue is that its status as a dietary supplement in the US is currently in dispute. The FDA has taken the position that NMN doesn’t qualify as a dietary supplement because it’s being investigated as a potential pharmaceutical—not because of any safety concerns. This has created some amount of regulatory uncertainty, but NMN products remain available in the US as discussions around its status continue.
No, the FDA’s action against NMN doesn’t mean it’s unsafe. The restriction is based on its investigation as a potential pharmaceutical drug—not due to any reported safety issues. In fact, high-quality NMN supplements have shown good safety profiles in clinical studies.
Yes, you can still buy NMN, just not as a dietary supplement on major platforms like Amazon. Reputable brands like Wonderfeel continue to sell NMN directly through their websites or other retailers, often with quality controls like clinical testing and GMP certification. Just be sure to buy from trusted sources.
