NMN and NAD Production: Why It’s So Important
The conversation with Dr. Salzman on Mark Hyman’s podcast kicks off with a quick discussion of how NMN produces NAD and the importance of NAD production for optimizing cellular health and, by extension, overall health. Here are some basics:
- Nicotinamide Mononucleotide (NMN) serves as a pivotal molecule in the biosynthesis of nicotinamide adenine dinucleotide (NAD), a crucial coenzyme involved in various cellular processes.
- NMN replenishes NAD levels within cells, particularly as individuals age and NAD naturally declines.
- Through intricate metabolic pathways, NMN facilitates the production of NAD in the body, serving as a key mediator in energy metabolism, DNA repair, and cellular signaling.
Understanding the synthesis of NAD from NMN sheds light on its significance in maintaining cellular health and offers potential avenues for therapeutic interventions aimed at combating age-related decline and various diseases associated with NAD deficiency.
Dr. Salzman elaborates on the importance of NAD in the human body, saying, “NAD is a critical factor in our energy. We now know it is involved in inflammation, it’s involved in pain, and as we get older, we’re all feeling a little bit more painful, and we’re also having loads of inflammation. We have more inflammatory diseases. So this deficit of NAD as we age is really causing a broad effect on our health.” Optimizing and encouraging the production of NAD in the human body is, thus, a crucial factor in maintaining and achieving overall health.
Controlling NAD Production Can Hold the Key to Preventative Care and Longevity
Not only do NAD levels affect inflammation, pain, and energy levels, but as Dr. Mark Hyman and Dr. Andrew Salzman discuss, “downstream” of these conditions are age-related illnesses, such as heart disease, cancer, diabetes, dementia, and more. It follows, then, that figuring out a way to naturally and safely encourage the production of NAD not only helps to make people feel better on a day to day basis, but holds at bay a slew of age-related ailments.
Salzman connects the importance of preventative medicine to addressing issues related to age and longevity: “Fundamentally, we need to slow and arrest or reverse this overriding inexorable aging process that is starting to degrade all of these different [bodily] pathways together. And so the search is now for more broad-spectrum or more fundamental approaches than just disease-specific ones. And as we look NAD story, what better candidate could there be than something that underlies energetics, pain, inflammation, immune risk?”
NR vs. NMN: Which is Better?
An important topic in the current discussion of NMN is its efficiency when compared to other NAD precursors like NR or Nicotinamide Riboside. While both NMN and NR serve as precursors for NAD synthesis, and studies are still being developed, they differ in their chemical structure and metabolic pathways, and Hyman suggests that NMN is coming out ahead. Salzman concurs, suggesting that while more research needs to be done, the studies coming out about NMN show that it is a particularly promising way to boost NAD levels in the human body.
Wonderfeel Youngr™ is an Excellent Choice for NMN Supplementation
The discussion between Dr. Hyman and Dr. Salzman ends with a more in-depth conversation about Wonderfeel Youngr™ supplements and their specific benefits for boosting NAD levels, longevity, and general well-being. Salzman explains that Wonderfeel Youngr™ supplements start from the premise that NMN is important and went on to develop and create a supplement that is completely safe and beneficial.
An added benefit of Wonderfeel Youngr™ supplements discussed in the podcast episode is its incorporation of the supportive polyphenol resveratrol, which can be found in the skin of grapes used to make red wine and has powerful antioxidant effects on cellular health. Additionally, Salzman discusses the fact that Youngr™ includes hydroxytyrosol, another polyphenol that can be found in olives and rare types of olive oil and has been linked to lower incidences of Alzheimer’s disease.
To listen to the podcast episode and hear more about the exciting frontiers being traversed with NMN supplementation, click here.